Gunnar K Gouras, MD

Professor of Experimental Neurology

Lund University, Lund, Sweden

I. The research group

 

 

II. Participation in the MADGIC project

 

 

III. Key publications relevant for the project

1. Edgar JR, Willén K, Gouras GK, Futter CE. ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular beta amyloid accumulation. J Cell Sci. 2015, in press.
2. Takahashi RH, Capetillo-Zarate E, Lin MT, Milner TA, Gouras GK. Accumulation of Intraneuronal ß- Amyloid 42 Peptides Is Associated with Early Changes in Microtubule-Associated Protein 2 in Neurites and Synapses. PLoS One; 8(1):e51965, 2013.
3. Capetillo-Zarate E, Gracia L, Yu F, Banfelder J, Lin MT, Tampellini D, Gouras GK. High-Resolution 3D Reconstruction Reveals Intra-Synaptic Amyloid Fibrils. Am J Pathol 179(5):2551-8, 2011.
4. Tampellini D, Rahman N, Lin MT, Capetillo-Zarate E, Gouras GK. Impaired β-amyloid secretion in Alzheimer's disease pathogenesis. J Neurosci, 31(43):15384-90, 2011.
5. Tampellini D, Capetillo-Zarate E, Dumont M, Huang Z, Yu F, Lin MT, Gouras GK. Effects of synaptic modulation on β-amyloid, synaptophysin and memory performance in Alzheimer's disease transgenic mice. J Neurosci 30(43):14299-304, 2010.